|Spoth R., Trudeau L., Shin C., Redmond C. (2008). Long-term effects of universal preventive interventions on prescription drug misuse. Addiction
Researchers tested the long-term effects of universal preventive interventions conducted during middle school on 17-21-year-olds' prescription drug misuse. Two randomized controlled prevention trials were conducted in public schools in the rural midwestern United States. In study 2, schools were assigned to the school-based Botvin LifeSkills Training (LST) plus a revised Iowa Strengthening Families Program (ISFP), called SFP 10-14 (LST + SFP 10-14), LST-only, or a control condition. LST + SFP 10-14 showed significant effects on life-time prescription drug misuse at the 11th-grade follow-up, while effects at the 12th-grade follow-up were marginally significant. Consistent with intervention effects on other substance use outcomes reported earlier, results suggest that universal interventions have potential for public health impact by reducing some types of prescription drug misuse among adolescents and young adults.